Jump to main content
Jump to site search


Novel three-fluorophore system as a ratiometric sensor for multiple proteases detection

Abstract

A synthetic three-fluorophore system with two enzymatically cleavable linkers has been developed for the simultaneous detection of two proteases in a mixture. The probe was designed to afford single excitation/triple emission ratiometric detection through fluorescence change during cleavage of a peptide linker. The developed assays were verified for trypsin and chymotrypsin as the model enzymes.

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Mar 2018, accepted on 14 May 2018 and first published on 14 May 2018


Article type: Communication
DOI: 10.1039/C8CC01731J
Citation: Chem. Commun., 2018, Accepted Manuscript
  •   Request permissions

    Novel three-fluorophore system as a ratiometric sensor for multiple proteases detection

    Y. Okorochenkova, M. Porubsky, S. Benicka and J. Hlaváč, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC01731J

Search articles by author

Spotlight

Advertisements