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Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR

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Abstract

Four variants of a synthetic chloride anion channel composed of dialkyamines linked to a heptapeptide have been studied in different lipid and polymer membranes using electrophysiological techniques. For the first time, the values of conductance states, voltage gating properties, and qualitative state transition frequency were measured in different lipid systems.

Graphical abstract: Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR

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Publication details

The article was received on 26 Feb 2018, accepted on 10 Apr 2018 and first published on 13 Apr 2018


Article type: Communication
DOI: 10.1039/C8CC01565A
Citation: Chem. Commun., 2018, Advance Article
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    Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR

    F. Minooei, M. D. Martin, J. R. Fried and J. P. Brian, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC01565A

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