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Metabolic Glycan Labeling-Assisted Discovery of Cell-Surface Markers for Primary Neural Stem and Progenitor Cells

Abstract

A chemical approach was developed for identifying cell-surface markers for primary neural stem cells (NSCs). metabolic labeling of sialoglycans with bioorthogonal functional groups. Using an in vitro coculture system of primary NSCs combined with metabolic lableing of sialoglycans with bioorthogonal functional groups, we selectively enriched and identified a list of cell-surface sialoglycoproteins that were more abundantly expressed in neural stem and progenitor cells.

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Publication details

The article was received on 24 Feb 2018, accepted on 16 Apr 2018 and first published on 16 Apr 2018


Article type: Communication
DOI: 10.1039/C8CC01535J
Citation: Chem. Commun., 2018, Accepted Manuscript
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    Metabolic Glycan Labeling-Assisted Discovery of Cell-Surface Markers for Primary Neural Stem and Progenitor Cells

    Q. Bai, L. Dong, Y. Hao, X. Chen and Q. Shen, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC01535J

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