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Issue 34, 2018
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Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

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Abstract

Encapsulation of ionic nanoparticles in a hydrogel microparticle, i.e. microgel, produces a target-stimulated probe for molecular detection. Selective reactive oxygen species (ROS) release the enclosed cations from the microgel which subsequently turn on the fluorogenic dyes to emit intense fluorescence, permitting rapid detection of ROS or ROS-producing molecules. The ROS-responsive microgel provides the advantages of simple fabrication, bright and stable signals, easy handling, and rapid response, carrying great promise in biomedical applications.

Graphical abstract: Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

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Publication details

The article was received on 21 Feb 2018, accepted on 27 Mar 2018 and first published on 28 Mar 2018


Article type: Communication
DOI: 10.1039/C8CC01432A
Citation: Chem. Commun., 2018,54, 4329-4332
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    Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

    Y. Liu, Y. Wang, S. Sedano, Q. Jiang, Y. Duan, W. Shen, J. Jiang and W. Zhong, Chem. Commun., 2018, 54, 4329
    DOI: 10.1039/C8CC01432A

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