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Issue 37, 2018
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Decorating an individual living cell with a shell of controllable thickness by cytocompatible surface initiated graft polymerization

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Abstract

Surface engineering of individual living cells is a promising field for cell-based applications. However, engineering individual cells with controllable thickness by chemical methods has been rarely studied. This article describes the development of a new cytocompatible chemical strategy to decorate individual living cells. The thicknesses of the crosslinked shells could be conveniently controlled by the irradiation time, visible light intensity, or monomer concentration. Moreover, the lag phase of the yeast cell division was extended and their stability against lysis was improved, which could also be tuned by controlling the shell thickness.

Graphical abstract: Decorating an individual living cell with a shell of controllable thickness by cytocompatible surface initiated graft polymerization

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Publication details

The article was received on 14 Feb 2018, accepted on 09 Apr 2018 and first published on 12 Apr 2018


Article type: Communication
DOI: 10.1039/C8CC01311J
Citation: Chem. Commun., 2018,54, 4677-4680
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    Decorating an individual living cell with a shell of controllable thickness by cytocompatible surface initiated graft polymerization

    G. Wang, K. Zhang, Y. Wang, C. Zhao, B. He, Y. Ma and W. Yang, Chem. Commun., 2018, 54, 4677
    DOI: 10.1039/C8CC01311J

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