Issue 20, 2018

Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

Abstract

A reductive dicarbofunctionalization reaction of alkenes has been developed and applied to the preparation of substituted carbo- and heterocycles. The reaction conditions avoid the use of air-sensitive organometallic reagents, and are compatible with a broad range of bromo-electrophiles and a wide variety of substituents to give cyclic products in excellent yields.

Graphical abstract: Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

Supplementary files

Article information

Article type
Communication
Submitted
16 Jan 2018
Accepted
15 Feb 2018
First published
15 Feb 2018

Chem. Commun., 2018,54, 2558-2561

Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

Y. Kuang, X. Wang, D. Anthony and T. Diao, Chem. Commun., 2018, 54, 2558 DOI: 10.1039/C8CC00358K

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