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Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

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Abstract

A reductive dicarbofunctionalization reaction of alkenes has been developed and applied to the preparation of substituted carbo- and heterocycles. The reaction conditions avoid the use of air-sensitive organometallic reagents, and are compatible with a broad range of bromo-electrophiles and a wide variety of substituents to give cyclic products in excellent yields.

Graphical abstract: Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

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Publication details

The article was received on 16 Jan 2018, accepted on 15 Feb 2018 and first published on 15 Feb 2018


Article type: Communication
DOI: 10.1039/C8CC00358K
Citation: Chem. Commun., 2018, Advance Article
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    Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

    Y. Kuang, X. Wang, D. Anthony and T. Diao, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC00358K

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