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Issue 21, 2018
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Red fluorescent probes for real-time imaging of the cell cycle by dynamic monitoring of the nucleolus and chromosome

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Abstract

Two cationic molecular rotors, 1 and 2, capable of real-time cell-cycle imaging by specifically dynamic monitoring of nucleolus and chromosome changes were developed. A further study shows that fluorescence enhancements in the nucleolus and chromosome are attributed to a combination effect of interaction with nucleic acid and high condensation of the nucleolus and chromosome.

Graphical abstract: Red fluorescent probes for real-time imaging of the cell cycle by dynamic monitoring of the nucleolus and chromosome

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Publication details

The article was received on 11 Jan 2018, accepted on 13 Feb 2018 and first published on 14 Feb 2018


Article type: Communication
DOI: 10.1039/C8CC00256H
Citation: Chem. Commun., 2018,54, 2635-2638
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    Red fluorescent probes for real-time imaging of the cell cycle by dynamic monitoring of the nucleolus and chromosome

    K. Wang, X. Chao, B. Liu, D. Zhou, L. He, X. Zheng, Q. Cao, C. Tan, C. Zhang and Z. Mao, Chem. Commun., 2018, 54, 2635
    DOI: 10.1039/C8CC00256H

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