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Issue 23, 2018
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Construction of tunable peptide nucleic acid junctions

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Abstract

We report here the construction of 3-way and 4-way peptide nucleic acid (PNA) junctions as basic structural units for PNA nanostructuring. The incorporation of amino acid residues into PNA chains makes PNA nanostructures with more structural complexity and architectural flexibility possible, as exemplified by building 3-way PNA junctions with tunable nanopores. Given that PNA nanostructures have good thermal and enzymatic stabilities, they are expected to have broad potential applications in biosensing, drug delivery and bioengineering.

Graphical abstract: Construction of tunable peptide nucleic acid junctions

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Publication details

The article was received on 05 Jan 2018, accepted on 12 Jan 2018 and first published on 19 Jan 2018


Article type: Communication
DOI: 10.1039/C8CC00108A
Citation: Chem. Commun., 2018,54, 2846-2849
  • Open access: Creative Commons BY license
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    Construction of tunable peptide nucleic acid junctions

    T. Duan, L. He, Y. Tokura, X. Liu, Y. Wu and Z. Shi, Chem. Commun., 2018, 54, 2846
    DOI: 10.1039/C8CC00108A

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