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Issue 20, 2018
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A simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions

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Abstract

We develop a simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions. This method enables one-step and one-tube detection of telomerase with a detection limit of 3 cells, and it can be further applied for the screening of telomerase inhibitors and the discrimination of cancer cells from normal cells.

Graphical abstract: A simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions

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Publication details

The article was received on 05 Jan 2018, accepted on 31 Jan 2018 and first published on 31 Jan 2018


Article type: Communication
DOI: 10.1039/C8CC00093J
Citation: Chem. Commun., 2018,54, 2483-2486
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    A simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions

    F. Ma, S. Wei, J. Leng, B. Tang and C. Zhang, Chem. Commun., 2018, 54, 2483
    DOI: 10.1039/C8CC00093J

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