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Surface functional DNA density control by programmable molecular defects

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Abstract

Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.

Graphical abstract: Surface functional DNA density control by programmable molecular defects

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Publication details

The article was received on 28 Dec 2017, accepted on 13 Feb 2018 and first published on 14 Feb 2018


Article type: Communication
DOI: 10.1039/C7CC09908H
Citation: Chem. Commun., 2018, Advance Article
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    Surface functional DNA density control by programmable molecular defects

    C. Chen, C. Wang, P. Chen and W. Liao, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC09908H

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