Jump to main content
Jump to site search

Issue 6, 2018
Previous Article Next Article

Amplified detection of genome-containing biological targets using terminal deoxynucleotidyl transferase-assisted rolling circle amplification

Author affiliations

Abstract

We proposed a terminal deoxynucleotidyl transferase (TdT)-assisted rolling circle amplification (RCA) strategy for the amplified detection of genome-containing biological targets. The synergetic signal amplification of DNase I-mediated genomic DNA fragmentation and subsequent RCA allow the sensing platform to have extraordinarily high sensitivity.

Graphical abstract: Amplified detection of genome-containing biological targets using terminal deoxynucleotidyl transferase-assisted rolling circle amplification

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Dec 2017, accepted on 19 Dec 2017 and first published on 19 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC09337C
Citation: Chem. Commun., 2018,54, 682-685
  •   Request permissions

    Amplified detection of genome-containing biological targets using terminal deoxynucleotidyl transferase-assisted rolling circle amplification

    Y. Du, Y. Zhu, X. Li and D. Kong, Chem. Commun., 2018, 54, 682
    DOI: 10.1039/C7CC09337C

Search articles by author

Spotlight

Advertisements