Issue 8, 2018

Universal absolute quantification of biomolecules using element mass spectrometry and generic standards

Abstract

We present a novel and highly sensitive ICP-MS approach for absolute quantification of all important target biomolecule containing P, S, Se, As, Br, and/or I (e.g., proteins and phosphoproteins, metabolites, pesticides, drugs), under the same simple instrumental conditions and without requiring any specific and/or isotopically enriched standard.

Graphical abstract: Universal absolute quantification of biomolecules using element mass spectrometry and generic standards

Supplementary files

Article information

Article type
Communication
Submitted
24 Nov 2017
Accepted
21 Dec 2017
First published
21 Dec 2017

Chem. Commun., 2018,54, 904-907

Universal absolute quantification of biomolecules using element mass spectrometry and generic standards

F. Calderón-Celis, A. Sanz-Medel and J. R. Encinar, Chem. Commun., 2018, 54, 904 DOI: 10.1039/C7CC09059E

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