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Issue 8, 2018
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Universal absolute quantification of biomolecules using element mass spectrometry and generic standards

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Abstract

We present a novel and highly sensitive ICP-MS approach for absolute quantification of all important target biomolecule containing P, S, Se, As, Br, and/or I (e.g., proteins and phosphoproteins, metabolites, pesticides, drugs), under the same simple instrumental conditions and without requiring any specific and/or isotopically enriched standard.

Graphical abstract: Universal absolute quantification of biomolecules using element mass spectrometry and generic standards

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Publication details

The article was received on 24 Nov 2017, accepted on 21 Dec 2017 and first published on 21 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC09059E
Citation: Chem. Commun., 2018,54, 904-907
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    Universal absolute quantification of biomolecules using element mass spectrometry and generic standards

    F. Calderón-Celis, A. Sanz-Medel and J. R. Encinar, Chem. Commun., 2018, 54, 904
    DOI: 10.1039/C7CC09059E

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