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A hydrogen fuel cell for rapid, enzyme-catalysed organic synthesis with continuous monitoring

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Abstract

A one-pot fuel cell for specific, enzyme-catalysed organic synthesis, with continuous monitoring of rate and reaction progress, combines an electrode catalysing rapid, reversible and diffusion-controlled interconversion of NADP+ and NADPH with a Pt electrode catalysing 2H+/H2 interconversion. This Communication demonstrates its performance and characteristics using the reductive amination of 2-oxoglutarate as a test system.

Graphical abstract: A hydrogen fuel cell for rapid, enzyme-catalysed organic synthesis with continuous monitoring

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Publication details

The article was received on 17 Nov 2017, accepted on 02 Jan 2018 and first published on 10 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC08859K
Citation: Chem. Commun., 2018, Advance Article
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    A hydrogen fuel cell for rapid, enzyme-catalysed organic synthesis with continuous monitoring

    L. Wan, C. F. Megarity, B. Siritanaratkul and F. A. Armstrong, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08859K

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