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Issue 6, 2018
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A highly fluorescent water soluble spirobifluorene dye with a large Stokes shift: synthesis, characterization and bio-applications

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Abstract

The first water-soluble spirobifluorene derivative has been synthesized, which exhibits high fluorescence quantum yield and a large Stokes shift (>100 nm). Proteins induce changes in the emission color, allowing to reach the nanomolar detection limit. Cellular uptake and cytotoxicity studies in living cells revealed its biocompatibility, indicating potential application for live cell imaging.

Graphical abstract: A highly fluorescent water soluble spirobifluorene dye with a large Stokes shift: synthesis, characterization and bio-applications

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Publication details

The article was received on 14 Nov 2017, accepted on 19 Dec 2017 and first published on 19 Dec 2017


Article type: Communication
DOI: 10.1039/C7CC08761F
Citation: Chem. Commun., 2018,54, 642-645
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    A highly fluorescent water soluble spirobifluorene dye with a large Stokes shift: synthesis, characterization and bio-applications

    F. Schlüter, K. Riehemann, N. S. Kehr, S. Quici, C. G. Daniliuc and F. Rizzo, Chem. Commun., 2018, 54, 642
    DOI: 10.1039/C7CC08761F

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