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Self-assembly of small-molecule fumaramides allows transmembrane chloride channel formation

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Abstract

This study reports the formation of self-assembled transmembrane anion channels by small-molecule fumaramides. Such artificial ion channel formation was confirmed by ion transport across liposomes and by planar bilayer conductance measurements. The geometry-optimized model of the channel and Cl ion selectivity within the channel lumen was also illustrated.

Graphical abstract: Self-assembly of small-molecule fumaramides allows transmembrane chloride channel formation

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Publication details

The article was received on 11 Nov 2017, accepted on 05 Jan 2018 and first published on 05 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC08693H
Citation: Chem. Commun., 2018, Advance Article
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    Self-assembly of small-molecule fumaramides allows transmembrane chloride channel formation

    A. Roy, A. Gautam, J. A. Malla, S. Sarkar, A. Mukherjee and P. Talukdar, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08693H

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