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Supramolecular protein cages constructed from a crystalline protein matrix

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Abstract

Protein crystals are formed via ordered arrangements of proteins, which assemble to form supramolecular structures. Here, we show a method for the assembly of supramolecular protein cages within a crystalline environment. The cages are stabilized by covalent cross-linking allowing their release via dissolution of the crystal. The high stability of the desiccated protein crystals allows cages to be constructed.

Graphical abstract: Supramolecular protein cages constructed from a crystalline protein matrix

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Publication details

The article was received on 11 Nov 2017, accepted on 29 Jan 2018 and first published on 29 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC08689J
Citation: Chem. Commun., 2018, Advance Article
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    Supramolecular protein cages constructed from a crystalline protein matrix

    H. Negishi, S. Abe, K. Yamashita, K. Hirata, K. Niwase, M. Boudes, F. Coulibaly, H. Mori and T. Ueno, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08689J

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