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Issue 10, 2018
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Absorbance enhancement of aptamers/GNP enables sensitive protein detection in rat brains

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Abstract

An absorbance enhanced probe based on gold nanoparticles (GNPs) was proposed for a protein assay in the cerebrospinal fluid of a rat brain. The GNPs, assembled with two aptamers by proximity ligation, have high anti-salt properties, and good selectivity and response toward proteins, such as interferon-gamma, in the brain.

Graphical abstract: Absorbance enhancement of aptamers/GNP enables sensitive protein detection in rat brains

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Publication details

The article was received on 09 Nov 2017, accepted on 05 Jan 2018 and first published on 05 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC08636A
Citation: Chem. Commun., 2018,54, 1193-1196
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    Absorbance enhancement of aptamers/GNP enables sensitive protein detection in rat brains

    J. Mao, M. Xu, W. Ji and M. Zhang, Chem. Commun., 2018, 54, 1193
    DOI: 10.1039/C7CC08636A

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