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Aldehyde-functionalized metal–organic frameworks for selective sensing of homocysteine over Cys, GSH and other natural amino acids

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Abstract

A novel aldehyde-functionalized porous metal–organic framework (MOF) material has been constructed that can act as the first example of MOF-implicated sensors for discriminating Hcy from natural amino acids and even thiol-related peptides (GSH) with high sensitivity (LOD = 40 nM). The sensing mechanism is also discussed.

Graphical abstract: Aldehyde-functionalized metal–organic frameworks for selective sensing of homocysteine over Cys, GSH and other natural amino acids

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Publication details

The article was received on 01 Nov 2017, accepted on 03 Jan 2018 and first published on 03 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC08414E
Citation: Chem. Commun., 2018, Advance Article
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    Aldehyde-functionalized metal–organic frameworks for selective sensing of homocysteine over Cys, GSH and other natural amino acids

    J. Wang, Y. Liu, M. Jiang, Y. Li, L. Xia and P. Wu, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08414E

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