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In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

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Abstract

A facile, general and turn-on nucleus imaging strategy was first developed based on in situ fluorescence activation of C-rich dark silver nanoclusters by G-rich telomeres. After a simple incubation without washing, nanoclusters could selectively stain the nucleus with intense red luminescence, which was confirmed using fixed/living cells and several cell lines.

Graphical abstract: In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

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Publication details

The article was received on 25 Oct 2017, accepted on 02 Jan 2018 and first published on 02 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC08228B
Citation: Chem. Commun., 2018, Advance Article
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    In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

    D. Li, Z. Qiao, Y. Yu, J. Tang, X. He, H. Shi, X. Ye, Y. Lei and K. Wang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC08228B

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