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Lighting-up protein–ligand interactions with fluorescent PET (photoinduced electron transfer) sensor designs

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Abstract

The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), is switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. Sensors 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations.

Graphical abstract: Lighting-up protein–ligand interactions with fluorescent PET (photoinduced electron transfer) sensor designs

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Publication details

The article was received on 29 Jul 2017, accepted on 23 Nov 2017 and first published on 27 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC05929A
Citation: Chem. Commun., 2018, Advance Article
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    Lighting-up protein–ligand interactions with fluorescent PET (photoinduced electron transfer) sensor designs

    B. McLaughlin, E. M. Surender, G. D. Wright, B. Daly and A. P. de Silva, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C7CC05929A

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