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Biocompatible alkyl cyanoacrylate and their derivatives as bio-adhesives

Abstract

Cyanoacrylate adhesives and their homologues have enticed interest over past few decades owing to applications in biomedical sector extending from tissue adhesive to scaffolds to implants to dental material and adhesives cause of its inherent biocompatibility and ability to polymerize solely on moisture owing to which it adheres itself to any substrate consisting moisture such as skin. The ability to tailor formulations of alkyl cyanoacrylate to form derivative compounds to meet application requisites along with their biodegradability in conjunction with their inherent biocompatibility make them highly sought candidates in biomedical sector. Extensive exploration on cyanoacrylate adhesives and their homologue systems in biomedical applications have been investigated but no consolidated literature of vast data is as such available. The aptitude of cyanoacrylate adhesives of curing at low temperatures and without requisites of any hardener which attributes in high strength bonding interaction between two non-amalgamating substrates by ease of dispersion and self-curing, avoiding curtailing of effective utilization of such adhesives in biomedical engineering applications as bio glue for amalgamating tissues, implants, scaffolds etc. This article consolidates copious cyanoacrylate adhesives and their derived systems which are functional in versatile biomedical engineering applications such as bio glue, dental material and adhesives and other potential applications.

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Publication details

The article was received on 15 Mar 2018, accepted on 09 May 2018 and first published on 15 May 2018


Article type: Review Article
DOI: 10.1039/C8BM00312B
Citation: Biomater. Sci., 2018, Accepted Manuscript
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    Biocompatible alkyl cyanoacrylate and their derivatives as bio-adhesives

    J. M. Korde and B. Kandasubramanian, Biomater. Sci., 2018, Accepted Manuscript , DOI: 10.1039/C8BM00312B

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