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Bio-inspired Drug Delivery Systems: An Emerging Platform for Targeted Cancer Therapy


The quest for an ideal cancer treatment has led to the exploration of a variety of platforms to facilitate highly desirable and efficient drug delivery. As most anticancer drugs possess therapeutic potency to destroy tumor cells, there is a need to steer the compounds to their required sites using site-specific drug delivery vehicles. This has inspired the investigation of various natural particulates and biomaterials for the purpose. Bio-inspired platforms that directly mimic natural components in the body have demonstrated their ability to serve as one of the most versatile and innovative drug delivery systems in cancer therapy and diagnosis. The primary advantage of the innovation lies on the fundamental changes in systemic biodistribution that non-native drug delivery does not possess. This review will provide a comprehensive understanding and a succinct evaluation of various intelligent bioinspired delivery platforms which have become prominent in recent studies. Recent innovative examples, their advantages and limitations as well as future clinical potential will also be thoroughly discussed.

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Publication details

The article was received on 12 Feb 2018, accepted on 26 Feb 2018 and first published on 02 Mar 2018

Article type: Review Article
DOI: 10.1039/C8BM00175H
Citation: Biomater. Sci., 2018, Accepted Manuscript
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    Bio-inspired Drug Delivery Systems: An Emerging Platform for Targeted Cancer Therapy

    G. M. Ngandeu Neubi, Y. Damoah-Opoku, X. Gu, Y. Han, J. Zhou and Y. Ding, Biomater. Sci., 2018, Accepted Manuscript , DOI: 10.1039/C8BM00175H

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