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Issue 6, 2018
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Horseradish peroxidase-catalyzed hydrogelation for biomedical applications

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Abstract

Hydrogels catalyzed by horseradish peroxidase (HRP) serve as an efficient and effective platform for biomedical applications due to their mild reaction conditions for cells, fast and adjustable gelation rate in physiological conditions, and an abundance of substrates as water-soluble biocompatible polymers. In this review, we highlight the tunable characteristics and use of the HRP-catalyzed hydrogels and provide a brief overview of various substrates employed in the HRP system for different biomedical applications of the resultant hydrogels. In addition, we discuss and summarize the biocompatibility, possible functionalization, and biofabrication process. Finally, the future prospective of the HRP crosslinking system is highlighted with biomedical applications.

Graphical abstract: Horseradish peroxidase-catalyzed hydrogelation for biomedical applications

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Publication details

The article was received on 15 Jan 2018, accepted on 13 Apr 2018 and first published on 17 Apr 2018


Article type: Review Article
DOI: 10.1039/C8BM00056E
Citation: Biomater. Sci., 2018,6, 1286-1298
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    Horseradish peroxidase-catalyzed hydrogelation for biomedical applications

    M. Khanmohammadi, M. B. Dastjerdi, A. Ai, A. Ahmadi, A. Godarzi, A. Rahimi and J. Ai, Biomater. Sci., 2018, 6, 1286
    DOI: 10.1039/C8BM00056E

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