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Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

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Abstract

Herein, we present a series of light-triggered porphyrin-based polymeric drug conjugates PSDTD-m for combined chemo-photodynamic therapy of cancer. The controlled release of a drug through a ROS-cleavable linker combined with photodynamic therapy showed enhanced anticancer efficacy, proving the effectiveness of this light triggered smart nanocarrier platform for enhancing the therapy efficacy.

Graphical abstract: Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

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Publication details

The article was received on 30 Nov 2017, accepted on 11 Feb 2018 and first published on 12 Feb 2018


Article type: Communication
DOI: 10.1039/C7BM01114H
Citation: Biomater. Sci., 2018, Advance Article
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    Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

    L. Liu, R. Wang, C. Wang, J. Wang, L. Chen and J. Cheng, Biomater. Sci., 2018, Advance Article , DOI: 10.1039/C7BM01114H

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