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Bone-targeting poly(ethylene sodium phosphate)

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Abstract

Poly(ethylene sodium phosphate) (PEP·Na) showed excellent cytocompatibility and in vivo bone affinity. Moreover, PEP·Na did not interact with thrombin, which is a coagulation-related protein. Because immobilization of therapeutic agents and imaging probes on PEP·Na is easily performed, PEP·Na is a promising polymer for bone-targeted therapies.

Graphical abstract: Bone-targeting poly(ethylene sodium phosphate)

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Publication details

The article was received on 12 Oct 2017, accepted on 17 Nov 2017 and first published on 21 Nov 2017


Article type: Communication
DOI: 10.1039/C7BM00930E
Citation: Biomater. Sci., 2018, Advance Article
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    Bone-targeting poly(ethylene sodium phosphate)

    Y. Iwasaki, A. Yokota, A. Otaka, N. Inoue, A. Yamaguchi, T. Yoshitomi, K. Yoshimoto and M. Neo, Biomater. Sci., 2018, Advance Article , DOI: 10.1039/C7BM00930E

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