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Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells

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Abstract

Hydrogen sulfide (H2S), being an important gaseous signaling molecule, has been gaining increasing attention for its involvement in a wide range of physiological processes. Herein, we developed a novel fluorescence turn-on nanoprobe for selective and sensitive detection of H2S based on graphene quantum dots (GQDs) conjugated with (2,4-dinitrophenoxy)tyrosine (DNPTYR). Taking advantage of its high fluorescence quantum yield, biocompatibility, photostability, and ease to be uptaken by cells, the GQD-based fluorescence probe was further employed for real-time monitoring of the triggered dynamic change of the intracellular H2S level in live cells.

Graphical abstract: Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells

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Publication details

The article was received on 05 Sep 2017, accepted on 31 Oct 2017 and first published on 01 Nov 2017


Article type: Paper
DOI: 10.1039/C7BM00818J
Citation: Biomater. Sci., 2018, Advance Article
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    Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells

    N. Li, A. Than, J. Chen, F. Xi, J. Liu and P. Chen, Biomater. Sci., 2018, Advance Article , DOI: 10.1039/C7BM00818J

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