Jump to main content
Jump to site search


A redox-responsive mesoporous silica based nanoplatform for in vitro tumor-specific fluorescence imaging and enhanced photodynamic therapy

Author affiliations

Abstract

In order to obtain an optimal therapeutic effect with minimal systemic toxicity, a redox-responsive mesoporous silica nanoparticle (MSN)-based platform modified with protoporphyrin IX (PpIX)-multifunctional peptides was synthesized as an intelligent theranostic agent carrier. This redox-responsive nanoplatform could release the theranostic agent under a glutathione stimulus, produce fluorescence recovery for tumor-specific fluorescence imaging and provide tumor-enhanced photodynamic therapy.

Graphical abstract: A redox-responsive mesoporous silica based nanoplatform for in vitro tumor-specific fluorescence imaging and enhanced photodynamic therapy

Back to tab navigation

Supplementary files

Publication details

The article was received on 31 Aug 2017, accepted on 22 Nov 2017 and first published on 22 Nov 2017


Article type: Communication
DOI: 10.1039/C7BM00793K
Citation: Biomater. Sci., 2018, Advance Article
  •   Request permissions

    A redox-responsive mesoporous silica based nanoplatform for in vitro tumor-specific fluorescence imaging and enhanced photodynamic therapy

    F. Yuan, J. Li, H. Cheng, X. Zeng and X. Zhang, Biomater. Sci., 2018, Advance Article , DOI: 10.1039/C7BM00793K

Search articles by author

Spotlight

Advertisements