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Recent advances on toner-based microfluidic devices for bioanalytical applications

Abstract

Toner-based microfluidic devices have emerged since 2003 as promising platforms for bioanalytical applications. The simplicity of the fabrication process, the low instrumental requirements and the global affordability of required consumables are some key features that encourage the use of this kind of substrate for chemical and biochemical assays. This review aims to cover the recent advances regarding the fabrication procedures involving the laser printing of microfluidic devices on polyester films as well as the association of printing, laser cut and laminate to create devices assembled in multiple layer architecture. Examples of applications involving electrophoresis, mixing, concentration, purification, extraction, amplification, use of rotation-driven fluidic transport, enzyme-linked immunoassays and colorimetric lateral assays on toner-based platforms will be presented and discussed. Lastly, the versatility of toner-based fabrication technique to enable the production of hydrophobic valves, droplet generator device, mimetic vein-on-a-chip and hybrid devices will be also covered

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Publication details

The article was received on 15 May 2018, accepted on 30 May 2018 and first published on 01 Jun 2018


Article type: Critical Review
DOI: 10.1039/C8AY01095A
Citation: Anal. Methods, 2018, Accepted Manuscript
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    Recent advances on toner-based microfluidic devices for bioanalytical applications

    E. F. M. Gabriel, B. Lucca, G. R..M Duarte and W. K. T. Coltro, Anal. Methods, 2018, Accepted Manuscript , DOI: 10.1039/C8AY01095A

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