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Issue 22, 2018
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Determination of Cu2+ and biothiols by novel red fluorescent hybrid nanoparticles

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Abstract

Red fluorescent hybrid nanoparticles (NPG@PFBD) have been designed and synthesized successfully. The NPG@PFBD nanoparticles are composed of a fluorescent semiconducting polymer (PFBD) and n-propyl gallate (NPG). Because of the coordination between the gallate and Cu2+, Cu2+ could attach to the hybrid nanoparticles and quench their fluorescence through photoinduced electron transfer (PET). In addition, in the presence of biothiols, such as glutathione (GSH), Cu2+ would bind to the thiol. The PET between the hybrid nanoparticles and Cu2+ was weakened, and the fluorescence signal of the nanoparticles was recovered. A facile detection method for Cu2+ and biothiols was therefore developed. The detection limit for Cu2+ and GSH was 40 nM and 90 nM, respectively. The proposed fluorescent hybrid nanoparticles have great potential application for Cu2+ and GSH detection in related biological fields.

Graphical abstract: Determination of Cu2+ and biothiols by novel red fluorescent hybrid nanoparticles

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Publication details

The article was received on 20 Mar 2018, accepted on 26 Apr 2018 and first published on 02 May 2018


Article type: Paper
DOI: 10.1039/C8AY00614H
Citation: Anal. Methods, 2018,10, 2560-2566
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    Determination of Cu2+ and biothiols by novel red fluorescent hybrid nanoparticles

    L. Zhang, Z. Wang, J. Hou, L. Lei, J. Li, J. Bai, H. Huang and Y. Li, Anal. Methods, 2018, 10, 2560
    DOI: 10.1039/C8AY00614H

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