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BODIPY-based carbon dots as fluorescent nanoprobes for sensing and imaging of extreme acidity

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Abstract

Two kinds of novel water-soluble carbon dots (CD-A and CD-B) were synthesized from 4-bora-3a,4a-diaza-s-indacene (BODIPY) derivatives, and their abilities for sensing pH under extremely acidic conditions were studied. The fluorescence of CD-A is linearly proportional to the extreme acidity range of 1.5–4.0 with a pKa of 2.90, while CD-B exhibits a linear response over the pH range of 1.0–4.0 with a pKa value of 2.63. In addition, both CD-A and CD-B were successfully applied to visualize extreme acidity in bacteria. The results demonstrate that CD-A and CD-B can serve as promising nanoprobes for the determination of extremely acidic pH values with excellent biological significance.

Graphical abstract: BODIPY-based carbon dots as fluorescent nanoprobes for sensing and imaging of extreme acidity

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Publication details

The article was received on 10 Feb 2018, accepted on 17 Mar 2018 and first published on 20 Mar 2018


Article type: Paper
DOI: 10.1039/C8AY00320C
Citation: Anal. Methods, 2018, Advance Article
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    BODIPY-based carbon dots as fluorescent nanoprobes for sensing and imaging of extreme acidity

    L. Qiao, J. Wang, M. Zheng and Z. Xie, Anal. Methods, 2018, Advance Article , DOI: 10.1039/C8AY00320C

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