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Issue 17, 2018
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A sensitive electrochemical sensor for ofloxacin based on a graphene/zinc oxide composite film

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Abstract

Herein, a facile and novel preparation strategy based on electrochemical techniques for the fabrication of an electrodeposited graphene (GR) and zinc oxide (ZnO) nanocomposite-modified electrode (ZnO/GR/GCE) was developed to determine ofloxacin. The ZnO/GR/GCE can greatly enhance the electron transfer process and decrease the impedance of the surface of the electrode. Moreover, the oxidation of ofloxacin was highly increased on this modified electrode. Under the optimal experimental conditions, the experiment results exhibited that the oxidation peak current was linearly proportional to the concentration of ofloxacin in the range of 1–100 μM with a detection limit of 0.33 μM (S/N = 3) and a sensitivity of 1399.86 μA mM−1 cm2. The results for the determination of ofloxacin in the real samples demonstrate that this proposed method would be suitable for the routine analysis of ofloxacin in clinical use.

Graphical abstract: A sensitive electrochemical sensor for ofloxacin based on a graphene/zinc oxide composite film

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Publication details

The article was received on 18 Jan 2018, accepted on 20 Mar 2018 and first published on 12 Apr 2018


Article type: Paper
DOI: 10.1039/C8AY00127H
Citation: Anal. Methods, 2018,10, 1961-1967
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    A sensitive electrochemical sensor for ofloxacin based on a graphene/zinc oxide composite film

    X. Si, Y. Wei, C. Wang, L. Li and Y. Ding, Anal. Methods, 2018, 10, 1961
    DOI: 10.1039/C8AY00127H

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