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Single-system based discriminative optical sensors: Different strategies and versatile applications

Abstract

Discriminative optical sensors with pattern recognition property and high-throughput ability have been widely developed as they can distinguish multiple chemically similar analytes. Compared to traditional sensor arrays composed of a series of sensor elements, single-system based discriminative sensors using an array of optical changes at different wavelengths to provide input signals have drawn intensive attention recently. On one hand, they can provide discrimination ability that is lack in using selective sensors; on the other hand, they can simplify the complex data acquisition process accompanied with multiple-element-based sensor arrays and reduce consumption of sensor samples. This tutorial review gives an overview of the development of single-system based discriminative optical sensors. Different strategies for construction of single-system based discriminative sensors including dynamic combinatorial libraries, cross-reactive conjugated polymers, DNA G-quadruplex ensembles, combinatorial fluorescent molecular sensors, and fluorophore/surfactant aggregate ensembles are particularly introduced.

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Publication details

The article was received on 06 Feb 2018, accepted on 11 Jun 2018 and first published on 13 Jun 2018


Article type: Tutorial Review
DOI: 10.1039/C8AN00235E
Citation: Analyst, 2018, Accepted Manuscript
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    Single-system based discriminative optical sensors: Different strategies and versatile applications

    J. Fan and L. Ding, Analyst, 2018, Accepted Manuscript , DOI: 10.1039/C8AN00235E

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