Jump to main content
Jump to site search


A novel analytical approach for the determination of parathion methyl in water: Quadrupole isotope dilution mass spectrometry-dispersive liquid-liquid microextraction using multivariate optimization

Abstract

Dispersive liquid-liquid microextraction was coupled with quadruple isotope dilution mass spectrometry for the sensitive and accurate determination of parathion methyl in water. The two methods were complimentary to each other, with DLLME preconcentrating the analyte for trace determination, and ID4MS maintaining the integrity of the method’s accuracy and precision. An experimental design was used to optimize the extraction process. Results from the design were evaluated with the analysis of variance to determine the statistical significance of main factors of extraction and interaction effects of these factors. A three point calibration blend and sample blend were prepared gravimetrically by spiking with isotopically labelled parathion methyl. All four blends were left to equilibrate for three hours, after which they were preconcentrated under the optimum extraction conditions. The percent recovery recorded by this method was 99.9%, and the percent relative standard deviation was 0.32%. These results validated the accuracy and precision of the combined method.

Back to tab navigation

Publication details

The article was accepted on 12 Jan 2018 and first published on 12 Jan 2018


Article type: Paper
DOI: 10.1039/C7AN02014G
Citation: Analyst, 2018, Accepted Manuscript
  •   Request permissions

    A novel analytical approach for the determination of parathion methyl in water: Quadrupole isotope dilution mass spectrometry-dispersive liquid-liquid microextraction using multivariate optimization

    D. S. Chormey, E. Öztürk Er, S. Erarpat, G. ÖZZEYBEK, B. Arı and S. Bakırdere, Analyst, 2018, Accepted Manuscript , DOI: 10.1039/C7AN02014G

Search articles by author

Spotlight

Advertisements