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Issue 7, 2018
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MoS2 nanohybrid as a fluorescence sensor for highly selective detection of dopamine

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Abstract

Fluorescence sensors for biologically active molecules are catching attention due to their good performance and simplicity. Herein, we report a fluorescence sensor for the selective and sensitive detection of dopamine (DA) in aqueous samples. MoS2 nanohybrid material composed of MoS2 quantum dots dispersed over MoS2 nanosheets (MoS2 QDNS) in alkaline medium was employed as the fluorescent probe. In the presence of DA, the photoluminescence intensity of MoS2 QDNS was quenched linearly with increasing concentration of the former. The quenching mechanism was found to operate via Förster resonance energy transfer (FRET), and the inner filter effect (IFE). The QDNS sensor demonstrates high selectivity towards DA, especially in the presence of ascorbic acid and uric acid, which are the most potential interference for DA in biological systems. The sensitivity of the system was as low as 0.9 nM and demonstrated two linear ranges from 2.5 nM to 5.0 μM and from 5.0 μM to 10.4 μM. The sensor demonstrated a remarkable ability in the analysis of real blood samples and showed excellent potential for visual detection.

Graphical abstract: MoS2 nanohybrid as a fluorescence sensor for highly selective detection of dopamine

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Publication details

The article was received on 27 Oct 2017, accepted on 26 Feb 2018 and first published on 13 Mar 2018


Article type: Paper
DOI: 10.1039/C7AN01770G
Citation: Analyst, 2018,143, 1691-1698
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    MoS2 nanohybrid as a fluorescence sensor for highly selective detection of dopamine

    N. Pallikkarathodi Mani, M. Ganiga and J. Cyriac, Analyst, 2018, 143, 1691
    DOI: 10.1039/C7AN01770G

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