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Issue 4, 2018
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Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of the polymer DNAzyme nanostructure

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Abstract

We herein report an efficient hybridization chain reaction (HCR)- and DNAzyme-based enzyme-free signal amplification for the detection of specific exosomal miRNAs in the culture medium of cancer cells and serum samples from cancer patients via the target-triggered self-assembly of the polymer DNAzyme nanostructure.

Graphical abstract: Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of the polymer DNAzyme nanostructure

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Publication details

The article was received on 06 Nov 2017, accepted on 06 Jan 2018 and first published on 08 Jan 2018


Article type: Communication
DOI: 10.1039/C7AN01691C
Citation: Analyst, 2018,143, 813-816
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    Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of the polymer DNAzyme nanostructure

    D. He, L. Hai, H. Wang, R. Wu and H. Li, Analyst, 2018, 143, 813
    DOI: 10.1039/C7AN01691C

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