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Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of polymer DNAzyme nanostructure

Abstract

We herein report an efficient hybridization chain reaction (HCR)- and DNAzyme-based enzyme-free signal amplification for the detection of specific exosomal miRNAs in culture medium of cancer cells and serum samples from cancer patients via the target-triggered self-assembly of polymer DNAzyme nanostructure.

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Publication details

The article was received on 06 Nov 2017, accepted on 06 Jan 2018 and first published on 08 Jan 2018


Article type: Communication
DOI: 10.1039/C7AN01691C
Citation: Analyst, 2018, Accepted Manuscript
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    Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of polymer DNAzyme nanostructure

    H. Li, D. He, L. Hai, H. Wang and R. Wu, Analyst, 2018, Accepted Manuscript , DOI: 10.1039/C7AN01691C

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