Jump to main content
Jump to site search


Recent advances in the use of microfluidic technologies for single cell analysis

Author affiliations

Abstract

The inherent heterogeneity in cell populations has become of great interest and importance as analytical techniques have improved over the past decades. With the advent of personalized medicine, understanding the impact of this heterogeneity has become an important challenge for the research community. Many different microfluidic approaches with varying levels of throughput and resolution exist to study single cell activity. In this review, we take a broad view of the recent microfluidic developments in single cell analysis based on microwell, microchamber, and droplet platforms. We cover physical, chemical, and molecular biology approaches for cellular and molecular analysis including newly emerging genome-wide analysis.

Graphical abstract: Recent advances in the use of microfluidic technologies for single cell analysis

Back to tab navigation

Publication details

The article was received on 13 Aug 2017, accepted on 25 Oct 2017 and first published on 26 Oct 2017


Article type: Critical Review
DOI: 10.1039/C7AN01346A
Citation: Analyst, 2018, Advance Article
  •   Request permissions

    Recent advances in the use of microfluidic technologies for single cell analysis

    T. W. Murphy, Q. Zhang, L. B. Naler, S. Ma and C. Lu, Analyst, 2018, Advance Article , DOI: 10.1039/C7AN01346A

Search articles by author

Spotlight

Advertisements