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Integration of polymers in the pore space of mesoporous nanocarriers for drug delivery

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Abstract

In the past decade, controlled integration of polymers in pore space regions (framework walls, pore surface, pore interior) of mesoporous nanocarriers with large surface areas and pore volumes has attracted considerable attention in drug delivery. The system constitutes great advances in multivalent specific interactions which increase the host–guest affinity or avidity in the confined pore space. Herein, we present and discuss the recent advances in the covalent and noncovalent incorporation of polymers into mesopores for drug-oriented delivery systems. The present challenges and new approaches towards functional drug–polymer–inorganic mesostructured hybrids are reviewed for a deeper understanding of the synergy of functions.

Graphical abstract: Integration of polymers in the pore space of mesoporous nanocarriers for drug delivery

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Publication details

The article was received on 24 Sep 2017, accepted on 19 Oct 2017 and first published on 19 Oct 2017


Article type: Review Article
DOI: 10.1039/C7TB02559A
Citation: J. Mater. Chem. B, 2017, Advance Article
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    Integration of polymers in the pore space of mesoporous nanocarriers for drug delivery

    J. Zhang and K. Cai, J. Mater. Chem. B, 2017, Advance Article , DOI: 10.1039/C7TB02559A

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