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Issue 44, 2017
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Coordination polymer hybridized Au nanocages: a nanoplatform for dual-modality imaging guided near-infrared driven photothermal therapy in vivo

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Abstract

Coordination polymer hybridized Au nanocages (AuNC@CPs) were prepared via a dialysis process by combining Au nanocages with a coordination polymer, which was derived from (pq)2Ir(Hdcbpy) and Dy(OOCCH3)3. After hybridization, the localized surface plasmon resonance (LSPR) peak of the AuNC@CPs exhibited an evident red shift in comparison with that of the Au nanocages, which was due to a variation in the dielectric constant caused by the coordination polymer. Notably, inspired by their excellent photothermal, photoacoustic, and magnetic properties in solution, AuNC@CPs were used for near-infrared (NIR)-driven photothermal therapy (PTT) guided by photoacoustic (PA) and magnetic resonance (MR) imaging in vivo. Owing to their remarkable performance, the AuNC@CPs would represent promising nanoprobes for theranostics.

Graphical abstract: Coordination polymer hybridized Au nanocages: a nanoplatform for dual-modality imaging guided near-infrared driven photothermal therapy in vivo

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Publication details

The article was received on 28 Aug 2017, accepted on 05 Oct 2017 and first published on 12 Oct 2017


Article type: Paper
DOI: 10.1039/C7TB02302B
Citation: J. Mater. Chem. B, 2017,5, 8761-8769
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    Coordination polymer hybridized Au nanocages: a nanoplatform for dual-modality imaging guided near-infrared driven photothermal therapy in vivo

    C. Yan, L. Cui, Q. Yang, X. Zhou, L. Pan, X. Zhang, H. Yang, Z. Zhou and S. Yang, J. Mater. Chem. B, 2017, 5, 8761
    DOI: 10.1039/C7TB02302B

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