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Coordination Polymer Hybridized Au Nanocages: a Nanoplatform for Dual-modality Imaging Guided Near-Infrared Driven Photothermal therapy in Vivo

Abstract

Coordination polymer hybridized Au nanocages (AuNC@CPs) were prepared via a dialysis process by combining Au nanocages with the coordination polymer which derived from (pq)2Ir(Hdcbpy) and Dy(OOCCH3)3. After the hybridization, the localized surface plasmon resonance (LSPR) peak of AuNC@CPs exhibited an obvious red shift compared with that of Au nanocages due to the dielectric constant’s variation caused by the coordination polymer. Notably, inspried by their excellent photothermal, photoacoustic, and magnetic properties in solution, AuNC@CPs were used for photoacoustic (PA) and magnetic reasonance (MR) imaging guided near-infrared (NIR) driven photothermal therapy (PTT) in vivo. Owing to all of the remarkable performances, AuNC@CPs would be one kind of promising nanoprobes for theranostics.

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Publication details

The article was received on 28 Aug 2017, accepted on 05 Oct 2017 and first published on 12 Oct 2017


Article type: Paper
DOI: 10.1039/C7TB02302B
Citation: J. Mater. Chem. B, 2017, Accepted Manuscript
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    Coordination Polymer Hybridized Au Nanocages: a Nanoplatform for Dual-modality Imaging Guided Near-Infrared Driven Photothermal therapy in Vivo

    C. Yan, L. Cui, Q. Yang, X. Zhou, L. Pan, X. Zhang, H. Yang, Z. Zhou and S. Yang, J. Mater. Chem. B, 2017, Accepted Manuscript , DOI: 10.1039/C7TB02302B

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