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Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

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Abstract

Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles, which have highly interesting properties for therapeutic delivery and imaging. Nanogels may also possess responsive properties, depending on the employed polymers, allowing controlled release of therapeutics or image contrast generation upon exposure to physical or (bio)chemical cues. In this review, polymer nanogels are explored for application in imaging as well as for controlled drug and gene delivery. Moreover, nanogels are explored as responsive biomaterials and future applications are highlighted.

Graphical abstract: Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

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Publication details

The article was received on 21 Aug 2017, accepted on 30 Nov 2017 and first published on 30 Nov 2017


Article type: Review Article
DOI: 10.1039/C7TB02239E
Citation: J. Mater. Chem. B, 2017, Advance Article
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    Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

    A. E. Ekkelenkamp, M. R. Elzes, J. F. J. Engbersen and J. M. J. Paulusse, J. Mater. Chem. B, 2017, Advance Article , DOI: 10.1039/C7TB02239E

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