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Issue 34, 2017
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Cellulose nanocrystals are effective in inhibiting host cell bacterial adhesion

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Abstract

The use of cellulose nanocrystals (CNCs) as a biomaterial able to inhibit host cell bacterial adhesion is described. Pre-incubation of E. coli ATCC 25922 with a suspension of 0.1% CNCs afforded a significant 2 log reduction of bacterial adhesion to the intestinal cell monolayer HT29. This effect could be attributed to the interaction between the CNCs and the bacterial cell surface as confirmed using fluorescence microscopy experiments.

Graphical abstract: Cellulose nanocrystals are effective in inhibiting host cell bacterial adhesion

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Publication details

The article was received on 17 Jul 2017, accepted on 04 Aug 2017 and first published on 07 Aug 2017


Article type: Communication
DOI: 10.1039/C7TB01923H
Citation: J. Mater. Chem. B, 2017,5, 7018-7020
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    Cellulose nanocrystals are effective in inhibiting host cell bacterial adhesion

    G. D'Orazio, L. Munizza, J. Zampolli, M. Forcella, L. Zoia, P. Fusi, P. Di Gennaro and B. La Ferla, J. Mater. Chem. B, 2017, 5, 7018
    DOI: 10.1039/C7TB01923H

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