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Zwitterion-coated ultrasmall iron oxide nanoparticles for enhanced T1-weighted magnetic resonance imaging applications

Abstract

We report a convenient strategy to prepare ultrasmall Fe3O4 nanoparticles (NPs) coated with zwitterion L-cysteine (Cys) for enhanced T1-weighted magnetic resonance (MR) imaging applications. The formed Fe3O4-PEG-Cys NPs possess antifouling property, good r1 relaxivity, excellent cytocompatibility and hemocompatibility, and are able to be used as a contrast agent for enhanced blood pool and tumor MR imaging.

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Publication details

The article was received on 11 Jun 2017, accepted on 10 Aug 2017 and first published on 10 Aug 2017


Article type: Communication
DOI: 10.1039/C7TB01588G
Citation: J. Mater. Chem. B, 2017, Accepted Manuscript
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    Zwitterion-coated ultrasmall iron oxide nanoparticles for enhanced T1-weighted magnetic resonance imaging applications

    D. Ma, J. Chen, Y. Luo, H. Wang and X. Shi, J. Mater. Chem. B, 2017, Accepted Manuscript , DOI: 10.1039/C7TB01588G

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