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Co-deposition towards mussel-inspired antifouling and antibacterial membranes by using zwitterionic polymer and silver nanoparticles

Abstract

Bacterial attachment and the subsequent colonization on the surfaces of bio-materials usually result in biofilm formation, and thus raising implants failure, inflammation and so on. Herein, a novel mussel-inspired antibacterial and antifouling membrane was designed via co-deposition of polydopamine (PDA) and zwitterionic polymer, followed by incorporating bactericidal silver nanoparticles (Ag NPs). Polyethyleneimine-graft-sulfobetaine methacrylate (PEI-SBMA) was firstly co-deposited onto polyethersulfone (PES) membrane surface via crosslinking with PDA to construct antifouling surface. Then, Ag NPs were in situ synthesized on the membrane surface without adding any external reducing agents. Elemental and morphological surface analyses confirmed the successful co-deposition of PEI-SBMA onto PES surface and the successful reduction of silver ions by the PDA layer. In addition, the PEI-SBMA could significantly reduce Ag NPs aggregation, and the modified surface exhibited sustained bactericidal activity and effective inhibition of bacterial adhesion. It demostrated that the proposed approach was straightforward to fabricate mussel-inspired antifouling and antibacterial membranes, which had a great potential to be used in biomedical fields.

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Publication details

The article was received on 06 Jun 2017, accepted on 05 Aug 2017 and first published on 08 Aug 2017


Article type: Paper
DOI: 10.1039/C7TB01516J
Citation: J. Mater. Chem. B, 2017, Accepted Manuscript
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    Co-deposition towards mussel-inspired antifouling and antibacterial membranes by using zwitterionic polymer and silver nanoparticles

    Y. Xie, C. Tang, Z. Wang, Y. Xu, W. Zhao, S. Sun and C. Zhao, J. Mater. Chem. B, 2017, Accepted Manuscript , DOI: 10.1039/C7TB01516J

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