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Technical synthesis and biomedical applications of graphene quantum dots


Graphene quantum dots (GQDs) have generated enormous excitement because of their superiority in chemical inertness, biocompatibility and low toxicity. Due to quantum confinement and edge effects, GQDs have excellent properties, attracting extensive attention from scientists in the field of chemistry, physics, materials, biology, and other interdisciplinary sciences. In this review, we aimed to present a comprehensive view on the synthesis of GQDs for biological applications. We highlighted the potential methods like acid oxidation, hydrothermal and solvothermal reactions, microwave-assisted methods, electrochemical oxidation, as well as pyrolysis and carbonization for successful preparation of GQDs. Meanwhile, four representative types of the biomedical applications based on GQDs, such as bioimaging, biosensing, drug delivery, and antimicrobial materials, were introduced and discussed in detail. This work will be highly useful for quickly getting knowledge and experience for synthesizing various GQDs, and develop advanced strategies for creating novel functional GQD-based nanomaterials for further applications in biomedicine, materials science, analytical science, and optical nanodevices.

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Publication details

The article was received on 19 Apr 2017, accepted on 12 May 2017 and first published on 12 May 2017

Article type: Review Article
DOI: 10.1039/C7TB01073G
Citation: J. Mater. Chem. B, 2017, Accepted Manuscript
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    Technical synthesis and biomedical applications of graphene quantum dots

    K. Li, W. Liu, Y. Ni, D. Li, D. Lin, Z. Su and G. Wei, J. Mater. Chem. B, 2017, Accepted Manuscript , DOI: 10.1039/C7TB01073G

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