Jump to main content
Jump to site search

Issue 32, 2017
Previous Article Next Article

Designing polymeric adhesives for antimicrobial materials: poly(ethylene imine) polymer, graphene, graphene oxide and molybdenum trioxide – a biomimetic approach

Author affiliations

Abstract

The synthesis of biocompatible polymers for coating applications has gained significant attention in recent years due to the increasing spread of infectious diseases via contaminated surfaces. One strategy to combat this problem is to apply antimicrobial coatings to surfaces prone to microbial contamination. This study presents a series of biomimetic polymers that can be used as adhesives to immobilize known antimicrobial agents on the surfaces as coatings. Several polymers containing dopamine methacrylate as co-polymers were synthesized and investigated as adhesives for the deposition of an antimicrobial polymer (polyethyleneimine) and antimicrobial nanoparticles (graphene, graphene oxide and molybdenum trioxide) onto glass surfaces. The results showed that different antimicrobials required different types of adhesives for effective coating. Overall, the coatings fabricated from these composites were shown to inactivate E. coli and B. subtilis within 1 h. These coatings were also effective to prevent biofilm growth and demonstrated to be non-toxic to the human corneal epithelial cell line (htCEpi). Leaching tests of the coatings proved that the coatings were stable under biological conditions.

Graphical abstract: Designing polymeric adhesives for antimicrobial materials: poly(ethylene imine) polymer, graphene, graphene oxide and molybdenum trioxide – a biomimetic approach

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Mar 2017, accepted on 10 May 2017 and first published on 10 May 2017


Article type: Paper
DOI: 10.1039/C7TB00722A
Citation: J. Mater. Chem. B, 2017,5, 6616-6628
  •   Request permissions

    Designing polymeric adhesives for antimicrobial materials: poly(ethylene imine) polymer, graphene, graphene oxide and molybdenum trioxide – a biomimetic approach

    H. N. Nguyen, E. T. Nadres, B. G. Alamani and D. F. Rodrigues, J. Mater. Chem. B, 2017, 5, 6616
    DOI: 10.1039/C7TB00722A

Search articles by author

Spotlight

Advertisements