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Dynamic Intracellular Tracking Nanoparticles via pH-evoked “Off-On” Fluorescence

Abstract

Dynamic tracking of nanoparticles in cells faced a big challenge due to quickly fluorescent quenching for traditional organic dyes. In this study, the pH-switchable probe spiropyran (SP) was introduced in poly(ethylene glycol) (PEG) via atom radical polymerization (ATRP) to construct expected “off-on” fluorescence nanoparticles. In acidic environment, ring-close form spiropyran (SP) can isomerize into ring-open form merocyanine (MC) and strong red fluorenence was emitted to efficiently dynamic track nanoparticles in cells

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Publication details

The article was accepted on 25 Mar 2017 and first published on 04 Apr 2017


Article type: Communication
DOI: 10.1039/C7TB00713B
Citation: J. Mater. Chem. B, 2017, Accepted Manuscript
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    Dynamic Intracellular Tracking Nanoparticles via pH-evoked “Off-On” Fluorescence

    T. Su, F. R. Cheng, J. Cao, J. Q. Yan, X. Y. Peng and B. He, J. Mater. Chem. B, 2017, Accepted Manuscript , DOI: 10.1039/C7TB00713B

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