Jump to main content
Jump to site search


Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine

Author affiliations

Abstract

The promising biomedical applications of graphene oxide (GO) have quickly catalyzed a generation of various GO-based functional composites with desirable nanostructures and composites to satisfy the specific biomedical applications of GO-based nanosystems. This comprehensive review summarizes and discusses the very recent developments in rational design, chemical fabrication and versatile biomedical applications of GO-based functional composites, including metal oxide–GO, metal–GO, fluorescent nanoparticles–GO, silica–GO, polymer–GO and other specific GO-based composite nanosystems. The integration of multi-components with GO is also discussed. Their versatile theranostic applications include diagnostic imaging-guided therapy (photothermal therapy, photodynamic therapy and chemotherapy), biosensing-based tumor detection, and synergistic therapy. The biocompatibility and biosafety of these promising GO-based nanocomposites are also briefly mentioned. Finally, the unresolved critical issues and challenges facing the design/fabrication/application of these unique GO-based functional nanocomposites are proposed to further promote their clinical translation. The unique multi-composition, nanostructure and unique theranostic performance of GO-based composites are highly expected to pave a new way for the development of highly efficient theranostic protocols/approaches for precise personalized biomedicine to benefit human health.

Graphical abstract: Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine

Back to tab navigation

Publication details

The article was received on 11 Mar 2017, accepted on 27 Apr 2017 and first published on 27 Apr 2017


Article type: Review Article
DOI: 10.1039/C7TB00680B
Citation: J. Mater. Chem. B, 2017, Advance Article
  •   Request permissions

    Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine

    Y. Zhou, X. Jing and Y. Chen, J. Mater. Chem. B, 2017, Advance Article , DOI: 10.1039/C7TB00680B

Search articles by author

Spotlight

Advertisements