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Issue 21, 2017
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A promising dual mode SPECT/CT imaging platform based on 99mTc-labeled multifunctional dendrimer-entrapped gold nanoparticles

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Abstract

Multifunctional 99mTc-labeled dendrimer-entrapped gold nanoparticles (99mTc-Au DENPs) were designed and synthesized. Our results show that the type of surface groups (acetyl or hydroxyl) significantly impact the biodistribution profile of the 99mTc-Au DENPs, thereby allowing for preferential SPECT/CT imaging of different organs.

Graphical abstract: A promising dual mode SPECT/CT imaging platform based on 99mTc-labeled multifunctional dendrimer-entrapped gold nanoparticles

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Publication details

The article was received on 25 Feb 2017, accepted on 09 May 2017 and first published on 10 May 2017


Article type: Communication
DOI: 10.1039/C7TB00543A
Citation: J. Mater. Chem. B, 2017,5, 3810-3815
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    A promising dual mode SPECT/CT imaging platform based on 99mTc-labeled multifunctional dendrimer-entrapped gold nanoparticles

    S. Wen, L. Zhao, Q. Zhao, D. Li, C. Liu, Z. Yu, M. Shen, J. Majoral, S. Mignani, J. Zhao and X. Shi, J. Mater. Chem. B, 2017, 5, 3810
    DOI: 10.1039/C7TB00543A

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