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Issue 13, 2017
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Electroconductive nanoengineered biomimetic hybrid fibers for cardiac tissue engineering

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Abstract

We report for the first time the preparation of a fibrous material composed of surface grafted spherical nanosilver and collagen using one-step electrospinning. The resulting composite showed comparable morphology to the control without nanosilver, but had improved electrical conductivity. Under electrical stimulation, fibrous materials containing nanosilver increased connexin-43 expression and proliferation of neonatal cardiomyocytes. Furthermore, composites containing nanosilver prevented biofilm formation but did not activate macrophages.

Graphical abstract: Electroconductive nanoengineered biomimetic hybrid fibers for cardiac tissue engineering

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Publication details

The article was received on 09 Feb 2017, accepted on 14 Mar 2017 and first published on 15 Mar 2017


Article type: Communication
DOI: 10.1039/C7TB00405B
Citation: J. Mater. Chem. B, 2017,5, 2402-2406
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    Electroconductive nanoengineered biomimetic hybrid fibers for cardiac tissue engineering

    S. Allison, M. Ahumada, C. Andronic, B. McNeill, F. Variola, M. Griffith, M. Ruel, V. Hamel, W. Liang, E. J. Suuronen and E. I. Alarcon, J. Mater. Chem. B, 2017, 5, 2402
    DOI: 10.1039/C7TB00405B

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